Temperature directly affects photosynthesis, respiration, and growth rate. Maintain suitable ranges for specific crop types. Humidity influences disease development and plant water status. Control within appropriate ranges to prevent Botrytis and powdery mildew. Light drives photosynthesis and affects plant morphology. Ensure adequate light for target crop's needs. CO2 enrichment can significantly enhance growth in sealed environments. Air circulation through proper ventilation maintains gas exchange and prevents disease.